Invention Grant
- Patent Title: Spiroindolinone pyrrolidines
- Patent Title (中): 螺吲哚啉酮吡咯烷
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Application No.: US12939234Application Date: 2010-11-04
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Publication No.: US08088815B2Publication Date: 2012-01-03
- Inventor: David Joseph Bartkovitz , Xin-Jie Chu , Qingjie Ding , Bradford James Graves , Nan Jiang , Jing Zhang , Zhuming Zhang
- Applicant: David Joseph Bartkovitz , Xin-Jie Chu , Qingjie Ding , Bradford James Graves , Nan Jiang , Jing Zhang , Zhuming Zhang
- Applicant Address: US NJ Nutley
- Assignee: Hoffman-La Roche Inc.
- Current Assignee: Hoffman-La Roche Inc.
- Current Assignee Address: US NJ Nutley
- Agent George W. Johnson; Patricia S. Rocha-Tramaloni
- Main IPC: A61K31/4015
- IPC: A61K31/4015 ; C07D487/10
Abstract:
There are provided compounds of the formula wherein X, Y and R1 to R8 are described herein along with the enantiomers, pharmaceutically acceptable salts and esters thereof. The compounds are useful as anticancer agents.
Public/Granted literature
- US20110130398A1 SPIROINDOLINONE PYRROLIDINES Public/Granted day:2011-06-02
Information query
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