Invention Grant
- Patent Title: Substituted tetracycline compounds for the treatment of malaria
- Patent Title (中): 用于治疗疟疾的取代四环素化合物
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Application No.: US10692563Application Date: 2003-10-24
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Publication No.: US08088820B2Publication Date: 2012-01-03
- Inventor: Michael Draper , Mark L. Nelson
- Applicant: Michael Draper , Mark L. Nelson
- Applicant Address: US MA Boston
- Assignee: Paratek Pharmaceuticals, Inc.
- Current Assignee: Paratek Pharmaceuticals, Inc.
- Current Assignee Address: US MA Boston
- Agency: Mintz Levin Cohn Ferris Glovsky and Popeo, P.C.
- Agent Ivor R. Elrifi; Heidi A. Erlacher
- Main IPC: A61K31/36
- IPC: A61K31/36 ; C07D317/50 ; C07D317/54 ; C07D317/58
Abstract:
This invention provides a method for treating or preventing malaria in a subject. The method includes administering to the subject an effective amount of a substituted tetracycline compound, such that malaria is treated or prevented. In one aspect, the invention relates to pharmaceutical compositions which include an effective amount of a tetracycline compound to treat malaria in a subject and a pharmaceutically acceptable carrier. The substituted tetracycline compounds of the invention can be used to in combination with one or more anti-malarial compounds or can be used to treat or prevent malaria which is resistant to one or more other anti-malarial compounds.
Public/Granted literature
- US20040242548A1 Substituted tetracycline compounds for the treatment of malaria Public/Granted day:2004-12-02
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