Invention Grant
US08088886B2 Lipoprotein associated phospholipase A2, inhibitors thereof and use of the same in diagnosis and therapy
失效
脂蛋白相关磷脂酶A2，其抑制剂及其在诊断和治疗中的应用
- Patent Title: Lipoprotein associated phospholipase A2, inhibitors thereof and use of the same in diagnosis and therapy
- Patent Title (中): 脂蛋白相关磷脂酶A2，其抑制剂及其在诊断和治疗中的应用
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Application No.: US10406156Application Date: 2003-04-02
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Publication No.: US08088886B2Publication Date: 2012-01-03
- Inventor: Colin Houston MacPhee , David Graham Tew
- Applicant: Colin Houston MacPhee , David Graham Tew
- Applicant Address: GB Middlesex
- Assignee: Smith-Kline Beecham P.L.C.
- Current Assignee: Smith-Kline Beecham P.L.C.
- Current Assignee Address: GB Middlesex
- Agency: Licata & Tyrrell P.C.
- Agent Keith R. McCollum
- Priority: GB9313144.9 19930625; GB9400413.2 19940111
- Main IPC: A61K38/00
- IPC: A61K38/00 ; A61K38/04 ; C07K2/00 ; C07K4/00 ; C07K5/00 ; C07K7/00 ; C07K14/00 ; C07K16/00 ; C07K17/00
Abstract:
The enzyme Lp-PLA2 in purified form, an isolated nucleic acid molecule encoding Lp-PLA2, the use of an inhibitor of the enzyme Lp-PLA2 in therapy and a method of screening compounds to identify those compounds which inhibit the enzyme.
Public/Granted literature
- US20030186421A1 Lipoprotein associated phospholipase A2, inhibitors thereof and use of the same in diagnosis and therapy Public/Granted day:2003-10-02
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