Invention Grant
- Patent Title: Methods for modulating IKKα activity
- Patent Title (中): 调节IKKα活性的方法
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Application No.: US12903600Application Date: 2010-10-13
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Publication No.: US08088915B2Publication Date: 2012-01-03
- Inventor: Jun Li , Xiang Li , Jianfei Yang , Kenneth B. Marcu
- Applicant: Jun Li , Xiang Li , Jianfei Yang , Kenneth B. Marcu
- Applicant Address: US CT Ridgefield
- Assignee: Boehringer Ingelheim Pharmaceuticals Inc.
- Current Assignee: Boehringer Ingelheim Pharmaceuticals Inc.
- Current Assignee Address: US CT Ridgefield
- Agent Michael P. Morris; Usha R. Patel; David A. Dow
- Main IPC: C07H21/02
- IPC: C07H21/02 ; C07H21/04
Abstract:
A method for modulating NF-κB dependent gene transcription in a cell comprised of modulating IKKα protein activity in the cell. The present invention also provides siRNA compositions and methods thereof for modulating NF-κB dependent gene transcription.
Public/Granted literature
- US20110112284A1 METHODS FOR MODULATING IKKALPHA ACTIVITY Public/Granted day:2011-05-12
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