Invention Grant
US08088920B2 3-trifluoromethyl-pyrazine-2-carboxylic acid amide derivatives as HDL-cholesterol raising agents
有权
3-三氟甲基 - 吡嗪-2-羧酸酰胺衍生物作为HDL-胆固醇升高剂
- Patent Title: 3-trifluoromethyl-pyrazine-2-carboxylic acid amide derivatives as HDL-cholesterol raising agents
- Patent Title (中): 3-三氟甲基 - 吡嗪-2-羧酸酰胺衍生物作为HDL-胆固醇升高剂
-
Application No.: US12404365Application Date: 2009-03-16
-
Publication No.: US08088920B2Publication Date: 2012-01-03
- Inventor: Paul Hebeisen , Constantinos G. Panousis , Stephan Roever , Matthew Wright
- Applicant: Paul Hebeisen , Constantinos G. Panousis , Stephan Roever , Matthew Wright
- Applicant Address: US NJ Nutley
- Assignee: Hoffmann-La Roche Inc.
- Current Assignee: Hoffmann-La Roche Inc.
- Current Assignee Address: US NJ Nutley
- Agent George W. Johnston; Patricia S. Rocha-Tramaloni; Gene J. Yao
- Priority: EP08153802 20080331
- Main IPC: A81K31/497
- IPC: A81K31/497 ; C07D241/00
Abstract:
The present invention relates to pyrazine derivatives of the formula and pharmaceutically acceptable salts thereof, wherein R1 to R8 are as defined in the description and claims for use as HDL-cholesterol raising agents in the treatment and/or prophylaxis of diseases or disorders that can be treated with such agents such as dyslipidemia.
Public/Granted literature
- US20090247550A1 3-TRIFLUOROMETHYL-PYRAZINE-2-CARBOXYLIC ACID AMIDE DERIVATIVES AS HDL-CHOLESTEROL RAISING AGENTS Public/Granted day:2009-10-01
Information query
