Invention Grant
- Patent Title: Cyclic-fused beta-lactones and their synthesis
- Patent Title (中): 循环稠合β-内酯及其合成
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Application No.: US11775216Application Date: 2007-07-09
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Publication No.: US08088923B2Publication Date: 2012-01-03
- Inventor: Daniel Romo , Huda Henry-Riyad , Changsuk Lee , Henry Nguyen , Vikram C. Purohit , Seongho Oh
- Applicant: Daniel Romo , Huda Henry-Riyad , Changsuk Lee , Henry Nguyen , Vikram C. Purohit , Seongho Oh
- Applicant Address: US TX College Station
- Assignee: The Texas A&M University System
- Current Assignee: The Texas A&M University System
- Current Assignee Address: US TX College Station
- Agency: Christensen O'Connor Johnson Kindness PLLC
- Main IPC: C07D471/02
- IPC: C07D471/02
Abstract:
The present invention provides a concise synthetic method for generating lactam-fused beta-lactones that feature, in some embodiments, a tertiary fused carbinol, quaternary carbons, and a reactive beta-lactone moiety available for further reactions. The present invention further provides compounds synthesized by this method as well as methods of using these compounds as inhibitors of the proteasome and fatty acid synthase.
Public/Granted literature
- US20090062547A1 CYCLIC-FUSED BETA-LACTONES AND THEIR SYNTHESIS Public/Granted day:2009-03-05
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