In a solid-state image pickup apparatus having a pixel array unit composed by two-dimensionally arranging pixels for detecting a physical quantity in a row-column manner, pixel signals of a plurality of systems having different sensitivities are read from the pixel array unit in an analog manner, the pixel signals of the plurality of systems are amplified at respective basis amplification rates when a gain setting of the analog pixel signals is lower than a predetermined gain, and a pixel signal of at least one system having a high sensitivity among the plurality of systems is amplified at a plurality of amplification rates including an amplification rate higher than a basis amplification rate of the system having the high sensitivity when the gain setting is equal to or higher than the predetermined gain.