Systems and methods to measure the performance of a de-jitter buffer are disclosed. In a described example, a method to measure adaptive de-jitter buffer performance includes transmitting a known audio signal via a plurality of packets over a packet-based network, recording a received signal based on the known audio signal, and analyzing the recorded signal to determine one or more of a lower de-jitter buffer size, an upper de-jitter buffer size, a de-jitter buffer expansion speed, or a de-jitter buffer contraction speed based on the recorded signal and the known signal. The example method further includes comparing the one or more of the lower de-jitter buffer size, the upper de-jitter buffer size, the expansion speed, or the contraction speed to a performance requirement, and correcting communication network performance based on the comparison.