Methods and apparatus utilizing media characterization of memory devices facilitate the development of signal processors for analyzing memory device outputs. Models are developed from capturing output of memory devices of the type utilizing analog signals to communicate data values of two or more bits of information. The models are used to generate signals representative of the expected output of a memory device having an input data pattern. Read channels and/or controllers then process those signals to determine an output data pattern. By comparing the output data pattern to the input data pattern, the accuracy of the signal processing can be gauged.