Invention Grant
- Patent Title: Needle assembly for use in delivering precise dosages of proteinaceous pharmaceutical compositions and methods for use of same
- Patent Title (中): 用于提供精确剂量的蛋白质药物组合物的针组件及其使用方法
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Application No.: US12943526Application Date: 2010-11-10
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Publication No.: US08092429B2Publication Date: 2012-01-10
- Inventor: Mehdi Gasmi , Elias T. Ketchum , Dominick A. Vacante
- Applicant: Mehdi Gasmi , Elias T. Ketchum , Dominick A. Vacante
- Applicant Address: US CA San Diego
- Assignee: Ceregene, Inc.
- Current Assignee: Ceregene, Inc.
- Current Assignee Address: US CA San Diego
- Agency: DLA Piper LLP (US)
- Main IPC: A61M5/178
- IPC: A61M5/178
Abstract:
The needle assembly of the invention is a quad-partite system for use with an arc-center stereotactic headframe that allows a clinician to deliver recombinant expression vectors through the needle assembly to targeted sites at exact depths in the brain. Methods for use of the needle assembly with a rube insert for the needle cannula that does not bind proteins, as in protein viral capsids, permit delivery of precise volumes of pharmaceutical compositions containing viral recombinant expression vectors for gene therapy.
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