Invention Grant
US08093045B2 Fed-batch cell culture methods using non-animal-based hydrolysates
有权
使用非动物的水解产物的补料分批细胞培养方法
- Patent Title: Fed-batch cell culture methods using non-animal-based hydrolysates
- Patent Title (中): 使用非动物的水解产物的补料分批细胞培养方法
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Application No.: US11901274Application Date: 2007-09-13
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Publication No.: US08093045B2Publication Date: 2012-01-10
- Inventor: Itzcoatl A. Pla , Joseph G. Matuck , John C. Fann , Christof Schulz , Nichole A. Roy , David F. Bruton , James McIntire , David Chang Yu-Hsiang , Thomas Seewoester
- Applicant: Itzcoatl A. Pla , Joseph G. Matuck , John C. Fann , Christof Schulz , Nichole A. Roy , David F. Bruton , James McIntire , David Chang Yu-Hsiang , Thomas Seewoester
- Applicant Address: US IL Abbott Park
- Assignee: Abbott Laboratories
- Current Assignee: Abbott Laboratories
- Current Assignee Address: US IL Abbott Park
- Agency: McCarter & English, LLP
- Agent Elizabeth A. Hanley, Esq.; Cristin Howley Cowles
- Main IPC: C12N5/07
- IPC: C12N5/07 ; C12N5/16 ; C12N5/00 ; C12N5/02 ; C12P1/00 ; C12P21/04
Abstract:
The invention describes improved methods and compositions for producing a recombinant protein, e.g., an antibody, in mammalian cell culture. In addition, the invention provides improved cell culture media, including improved production media, feed solutions, and combination feeds, which may be used to improve protein productivity in mammalian cell culture.
Public/Granted literature
- US20080227136A1 Cell culture improvements Public/Granted day:2008-09-18
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