Invention Grant
US08093218B2 Peptide derived from vascular endothelial growth factor receptor-1 binding integrin α5β1 having proangiogenic activity
失效
来自血管内皮生长因子受体-1结合整合素α5和bgr的肽1具有促血管生成活性
- Patent Title: Peptide derived from vascular endothelial growth factor receptor-1 binding integrin α5β1 having proangiogenic activity
- Patent Title (中): 来自血管内皮生长因子受体-1结合整合素α5和bgr的肽1具有促血管生成活性
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Application No.: US12375775Application Date: 2007-07-31
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Publication No.: US08093218B2Publication Date: 2012-01-10
- Inventor: Stefania D'Atri , Cristina Maria Failla , Pedro Miguel Lacal , Angela Orecchia , Giovanna Zambruno , Anna Tramontano , Simonetta Soro , Veronica Morea
- Applicant: Stefania D'Atri , Cristina Maria Failla , Pedro Miguel Lacal , Angela Orecchia , Giovanna Zambruno , Anna Tramontano , Simonetta Soro , Veronica Morea
- Applicant Address: IT Rome IT Rome IT Rome
- Assignee: Provincia Italiana della Congregazione dei Figli dell'Immacolata Concezione-Istituto Dermopatico dell'Immacolata,Consiglio Nazionale delle Richerche,Universita' degli Studi di Roma “La Sapienza”
- Current Assignee: Provincia Italiana della Congregazione dei Figli dell'Immacolata Concezione-Istituto Dermopatico dell'Immacolata,Consiglio Nazionale delle Richerche,Universita' degli Studi di Roma “La Sapienza”
- Current Assignee Address: IT Rome IT Rome IT Rome
- Agency: Young & Thompson
- Priority: ITRM2006A000409 20060731
- International Application: PCT/IT2007/000551 WO 20070731
- International Announcement: WO2008/015720 WO 20080207
- Main IPC: A61K38/08
- IPC: A61K38/08 ; C07K7/06
Abstract:
Description of a sequence peptide isolated in the domain II type-immunoglobulin (Type-Ig) of the Vascular Endothelial Growth Factor receptor 1 (VEGF-1) binding integrin α5β1, usable for the preparation of pharmacological agents having proangiogenic activity.
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