Invention Grant
- Patent Title: Antisense modulation of C-reactive protein expression
- Patent Title (中): C-反应蛋白表达的反义调制
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Application No.: US13019190Application Date: 2011-02-01
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Publication No.: US08093224B2Publication Date: 2012-01-10
- Inventor: Rosanne M. Crooke , Mark J. Graham
- Applicant: Rosanne M. Crooke , Mark J. Graham
- Applicant Address: US CA Carlsbad
- Assignee: Isis Pharmaceuticals, Inc.
- Current Assignee: Isis Pharmaceuticals, Inc.
- Current Assignee Address: US CA Carlsbad
- Agency: Isis Pharmaceuticals, Inc. Patent Dept
- Main IPC: A61K31/70
- IPC: A61K31/70 ; C07H21/02 ; C07H21/04 ; C12Q1/68
Abstract:
Antisense compounds, compositions and methods are provided for modulating the expression of C-reactive protein. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding C-reactive protein. Methods of using these compounds for modulation of C-reactive protein expression and for treatment of diseases associated with expression of C-reactive protein are provided.
Public/Granted literature
- US20110117646A1 ANTISENSE MODULATION OF C-REACTIVE PROTEIN EXPRESSION Public/Granted day:2011-05-19
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