Invention Grant
- Patent Title: Dibenzo[b,f][1,4]oxazapine compounds
- Patent Title (中): 二苯并[b,f] [1,4]恶唑氮化合物
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Application No.: US12047858Application Date: 2008-03-13
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Publication No.: US08093237B2Publication Date: 2012-01-10
- Inventor: Cyrus Becker , Courtney Rubens , Jason Adams , Monica Palme , Pascal Druzgala
- Applicant: Cyrus Becker , Courtney Rubens , Jason Adams , Monica Palme , Pascal Druzgala
- Applicant Address: US CA Fremont
- Assignee: ARYx Therapeutics, Inc.
- Current Assignee: ARYx Therapeutics, Inc.
- Current Assignee Address: US CA Fremont
- Agency: McDonnell Boehnen Hulbert & Berghoff LLP
- Main IPC: A61P25/00
- IPC: A61P25/00 ; A61K31/553 ; C07D267/02
![Dibenzo[b,f][1,4]oxazapine compounds](/abs-image/US/2012/01/10/US08093237B2/abs.jpg.150x150.jpg)
Abstract:
The present invention relates to 11-(piperazin-1-yl)dibenzo[b,f][1,4 ]oxazapine compounds of the formula: where the variables are as defined herein, their salts and pharmaceutically acceptable compositions thereof. Methods of preparing these compounds are also described. These compounds may be used in the treatment of disorders such as schizophrenia, treatment resistant schizophrenia, bipolar disorder, psychotic depression, treatment resistant depression, schizophrenia-associated depression, treatment resistant OCD, autism, senile psychosis, psychotic dementia, L-DOPA induced psychosis, psychogenic polydipsia, psychotic symptoms of neurological disorders, sleep disorders.
Public/Granted literature
- US20080255088A1 DIBENZO[b,f][1,4]OXAZAPINE COMPOUNDS Public/Granted day:2008-10-16
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