Invention Grant
US08093256B2 Use of 8-substituted-6,7,8,9-tetrahydropyrimido[1,2-a] pyrimidin-4-one derivatives
失效
8-取代-6,7,8,9-四氢嘧啶并[1,2-a]嘧啶-4-酮衍生物的用途
![Use of 8-substituted-6,7,8,9-tetrahydropyrimido[1,2-a] pyrimidin-4-one derivatives](/docs/US/2012-01-10/US08093256B2/abs.jpg.600x600.jpg)
- Patent Title: Use of 8-substituted-6,7,8,9-tetrahydropyrimido[1,2-a] pyrimidin-4-one derivatives
- Patent Title (中): 8-取代-6,7,8,9-四氢嘧啶并[1,2-a]嘧啶-4-酮衍生物的用途
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Application No.: US11764374Application Date: 2007-06-18
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Publication No.: US08093256B2Publication Date: 2012-01-10
- Inventor: Alistair Lochead , Mourad Saady , Franck Slowinski , Philippe Yaiche
- Applicant: Alistair Lochead , Mourad Saady , Franck Slowinski , Philippe Yaiche
- Applicant Address: FR Paris JP Osaka
- Assignee: Sanofi-Aventis,Mitsubishi Pharma Corporation
- Current Assignee: Sanofi-Aventis,Mitsubishi Pharma Corporation
- Current Assignee Address: FR Paris JP Osaka
- Agent Kelly L. Bender
- Priority: EP03290727 20030321
- Main IPC: A61K31/519
- IPC: A61K31/519 ; C07D487/04
![Use of 8-substituted-6,7,8,9-tetrahydropyrimido[1,2-a] pyrimidin-4-one derivatives](/abs-image/US/2012/01/10/US08093256B2/abs.jpg.150x150.jpg)
Abstract:
The invention relates to use of substituted-pyrimidone derivatives represented by formula (I) or a salt thereof: wherein X, Y, R1, R2, R3, R4, R5, n, p and q are as defined herein. More specifically, the invention relates to a medicament comprising the said derivative or a salt thereof as an active ingredient which is used for preventive and/or therapeutic treatment of a disease caused by abnormal activity of GSK3β, such as Pick's disease among various other diseases as claimed herein.
Public/Granted literature
- US20080021046A1 USE OF 8-SUBSTITUTED-6,7,8,9-TETRAHYDROPYRIMIDO[1,2-a] PYRIMIDIN-4-ONE DERIVATIVES Public/Granted day:2008-01-24
Information query
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