Invention Grant
US08093264B2 Fused heterocycles as inhibitors of VEGF receptor and HGF receptor signaling
有权
融合杂环作为VEGF受体和HGF受体信号传导的抑制剂
- Patent Title: Fused heterocycles as inhibitors of VEGF receptor and HGF receptor signaling
- Patent Title (中): 融合杂环作为VEGF受体和HGF受体信号传导的抑制剂
-
Application No.: US11438133Application Date: 2006-05-19
-
Publication No.: US08093264B2Publication Date: 2012-01-10
- Inventor: Oscar Mario Saavedra , Stephen William Claridge , Lijie Zhan , Franck Raeppel , Arkadii Vaisburg , Stephane Raeppel , Michael Mannion , Frederic Gaudette , Ljubomir Isakovic , Marie-Claude Granger , Naomy Bernstein
- Applicant: Oscar Mario Saavedra , Stephen William Claridge , Lijie Zhan , Franck Raeppel , Arkadii Vaisburg , Stephane Raeppel , Michael Mannion , Frederic Gaudette , Ljubomir Isakovic , Marie-Claude Granger , Naomy Bernstein
- Applicant Address: CA St. Laurent, Quebec
- Assignee: Methylgene Inc.
- Current Assignee: Methylgene Inc.
- Current Assignee Address: CA St. Laurent, Quebec
- Agency: Wood, Phillips, Katz, Clark & Mortimer
- Main IPC: A01N43/42
- IPC: A01N43/42
Abstract:
The invention relates to the inhibition of VEGF receptor signaling and HGF receptor signaling. The invention provides compounds of general formula (A) wherein A1 is sulfur, A3 is CH, A2 is CH, D is heterocycle, Z is oxygen, SO0-2 or NR, Ar is phenyl and G is not a ring, and methods for inhibiting VEGF receptor signaling and HGF receptor signaling. The invention also provides compositions and methods for treating cell proliferative diseases and conditions.
Public/Granted literature
- US20070004675A1 Inhibitors of VEGF receptor and HGF receptor signaling Public/Granted day:2007-01-04
Information query
IPC分类:
