Invention Grant
- Patent Title: Genipin derivatives and uses thereof
- Patent Title (中): 栀子衍生物及其用途
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Application No.: US12622296Application Date: 2009-11-19
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Publication No.: US08093288B2Publication Date: 2012-01-10
- Inventor: Chen-Yu Zhang , Bradford B. Lowell , John A Porco, Jr. , Ruichao Shen , Cheng T. Lin , Stefan Krauss
- Applicant: Chen-Yu Zhang , Bradford B. Lowell , John A Porco, Jr. , Ruichao Shen , Cheng T. Lin , Stefan Krauss
- Applicant Address: US MA Boston US MA Boston
- Assignee: Beth Israel Deaconess Medical Center,Trustees of Boston University
- Current Assignee: Beth Israel Deaconess Medical Center,Trustees of Boston University
- Current Assignee Address: US MA Boston US MA Boston
- Agency: Hamilton, Brook, Smith & Reynolds, P.C.
- Main IPC: A61K31/35
- IPC: A61K31/35 ; A61K31/352 ; A61K31/365

Abstract:
Genipin derivatives and pharmaceutical compositions thereof that inhibit the activity of uncoupling protein-2 (UCP2) and are useful in treating deficient first-phase insulin secretion, non-insulin dependent diabetes mellitus, and ischemia in a mammal are disclosed.
Public/Granted literature
- US20100168160A1 Genipin Derivatives and Uses Thereof Public/Granted day:2010-07-01
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