Invention Grant
- Patent Title: Formulations of suberoylanilide hydroxamic acid and methods for producing the same
- Patent Title (中): 辛二酰苯胺异羟肟酸的制剂及其制备方法
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Application No.: US11663165Application Date: 2006-05-16
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Publication No.: US08093295B2Publication Date: 2012-01-10
- Inventor: Jeannie Chow Wong , Benjamin Max Cohen , Aaron S. Cote , Erik A. Dienemann , Kimberly Gallagher , Craig Ikeda , Justin Moser , Pavol Rajniak , Robert A. Reed , Brian Sell , Cindy Starbuck , Hsien-Hsin Tung , Qingxi Wang , Vincent R. Capodanno
- Applicant: Jeannie Chow Wong , Benjamin Max Cohen , Aaron S. Cote , Erik A. Dienemann , Kimberly Gallagher , Craig Ikeda , Justin Moser , Pavol Rajniak , Robert A. Reed , Brian Sell , Cindy Starbuck , Hsien-Hsin Tung , Qingxi Wang , Vincent R. Capodanno
- Applicant Address: US NJ Rahway
- Assignee: Merck Sharp & Dohme Corp.
- Current Assignee: Merck Sharp & Dohme Corp.
- Current Assignee Address: US NJ Rahway
- Agent Li Su; David A. Muthard
- International Application: PCT/US2006/018795 WO 20060516
- International Announcement: WO2006/127321 WO 20061130
- Main IPC: A61K31/19
- IPC: A61K31/19

Abstract:
The present invention provides a pharmaceutical composition or crystalline composition with a specific dissolution profile, which comprises suberoylanilide hydroxamic acid or a pharmaceutically acceptable salt or hydrate thereof as an active ingredient. The present invention provides a process of producing said crystalline composition or pharmaceutical composition. The present invention also provides compositions with a specific particle size distribution.
Public/Granted literature
- US20080132575A1 Formulations Of Suberoylanilide Hydroxamic Acid And Methods For Producing Same Public/Granted day:2008-06-05
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