Invention Grant
- Patent Title: Anti-perp antibody
- Patent Title (中): 抗perp抗体
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Application No.: US11628745Application Date: 2005-06-07
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Publication No.: US08093361B2Publication Date: 2012-01-10
- Inventor: Atsushi Ochiai , Norihiko Shiraishi , Yoko Kato , Toshio Ota , Susume Sekine , Kenya Shitara , Akiko Furuya , So Ohta , Emi Hosaka , Yuka Sasaki
- Applicant: Atsushi Ochiai , Norihiko Shiraishi , Yoko Kato , Toshio Ota , Susume Sekine , Kenya Shitara , Akiko Furuya , So Ohta , Emi Hosaka , Yuka Sasaki
- Applicant Address: JP Tokyo JP Tokyo
- Assignee: Kyowa Hakko Kirin Co., Ltd,Japan as represented by President of National Cancer Center
- Current Assignee: Kyowa Hakko Kirin Co., Ltd,Japan as represented by President of National Cancer Center
- Current Assignee Address: JP Tokyo JP Tokyo
- Agency: Sughrue Mion, PLLC
- Priority: JP2004-168116 20040607
- International Application: PCT/JP2005/010405 WO 20050607
- International Announcement: WO2005/121338 WO 20051222
- Main IPC: C07K16/00
- IPC: C07K16/00 ; C12P21/08 ; A61K39/395 ; A61K39/00 ; C12P21/04 ; G01N33/53 ; G01N33/574
Abstract:
The present invention provides an antibody which specifically recognizes three-dimensional structure of an extracellular region of a polypeptide encoded by PERP (p53 apoptosis effector related to PMP-22) gene and binds to the extracellular region. The antibody of the present invention is useful for treatment of various diseases which highly expresses a polypeptide encoded by the PERP gene. Also, a polypeptide encoded by the PERP gene or a cell expressing the polypeptide can be specifically detected by an immunological method using the antibody, so that the antibody is useful for diagnosis of various diseases related to PERP.
Public/Granted literature
- US20090258007A1 Anti-Perp Antibody Public/Granted day:2009-10-15
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