Invention Grant
- Patent Title: Anti-PERP recombinant antibody
- Patent Title (中): 抗PERP重组抗体
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Application No.: US11634209Application Date: 2006-12-06
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Publication No.: US08093362B2Publication Date: 2012-01-10
- Inventor: Atsushi Ochiai , Emi Hosaka , Kazuyasu Nakamura , Akiko Furuya , Yuji Ohki
- Applicant: Atsushi Ochiai , Emi Hosaka , Kazuyasu Nakamura , Akiko Furuya , Yuji Ohki
- Applicant Address: JP Tokyo JP Tokyo
- Assignee: Kyowa Hakko Kirin Co., Ltd.,Japan as Represented by President of National Cancer Center
- Current Assignee: Kyowa Hakko Kirin Co., Ltd.,Japan as Represented by President of National Cancer Center
- Current Assignee Address: JP Tokyo JP Tokyo
- Agency: Sughrue Mion, PLLC
- Priority: JPP.2005-352297 20051206
- Main IPC: C07K16/00
- IPC: C07K16/00 ; C12P21/08 ; C12P21/04 ; A61K39/395 ; A61K39/00
Abstract:
An antibody which binds to a polypeptide encoded by human PERP (p53 apoptosis effector related to PMP-22) gene which is considered to be related to incidence of cancer or the like is desired. The present invention provides a gene recombinant antibody which has no consensus sequence of an N-linked sugar chain in a variable region, specifically recognizes three-dimensional structure of an extracellular region of a polypeptide encoded by the PERP gene and binds to the extracellular region. The antibody is useful for treatment of various diseases expressing a polypeptide encoded by the PERP gene.
Public/Granted literature
- US20080267953A1 Anti-perp recombinant antibody Public/Granted day:2008-10-30
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