Invention Grant
- Patent Title: Thioaryl substituted inhibitors of zinc proteases and their use
- Patent Title (中): 硫代吡啶取代的锌蛋白酶抑制剂及其用途
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Application No.: US12309701Application Date: 2007-07-25
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Publication No.: US08093386B2Publication Date: 2012-01-10
- Inventor: Armando Rossello , Elisabetta Orlandini , Aldo Balsamo , Laura Panelli , Elisa Nuti
- Applicant: Armando Rossello , Elisabetta Orlandini , Aldo Balsamo , Laura Panelli , Elisa Nuti
- Applicant Address: IT Milan
- Assignee: Bracco Imaging S.p.A
- Current Assignee: Bracco Imaging S.p.A
- Current Assignee Address: IT Milan
- Agent M. Caragh Noone
- Priority: ITTO2006A0575 20060802
- International Application: PCT/EP2007/057661 WO 20070725
- International Announcement: WO2008/015139 WO 20080207
- Main IPC: C07D207/40
- IPC: C07D207/40 ; C07D209/48 ; C07D211/40 ; C07D211/54 ; C07D239/02 ; C07C57/13 ; C07C259/04 ; C07C311/10 ; A61K31/18 ; A61K31/19 ; A61K31/40 ; A61K31/445 ; A61K31/515

Abstract:
There are described compounds having the general formula (I) below and their pharmaceutically acceptable salts thereof, wherein E, X, m, q, R1, R2, n and ZBG have the meanings reported in the description useful, in therapy, as inhibitors of zinc metalloproteinases.
Public/Granted literature
- US20090239829A1 THIOARYL SUBSTITUTED INHIBITORS OF ZINC PROTEASES AND THEIR USE Public/Granted day:2009-09-24
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