A method and apparatus for performing closed loop transmit power control of a fractional dedicated physical channel (F-DPCH) are disclosed. Transmit power control (TPC) symbols on an F-DPCH and common pilot channel (CPICH) symbols are received. A short term signal power estimate is calculated using the TPC symbols, and a short term noise power estimate is calculated using the CPICH symbols. A short term signal-to-interference ratio (SIR) on the F-DPCH is calculated. A long term signal power estimate and a long term noise power estimate are calculated using the TPC symbols. A long term SIR is calculated and compared to a TPC quality target. An SIR target is adjusted based on comparison of the long term SIR to the TPC quality target. The short term SIR is compared to the SIR target and a TPC command is generated based on comparison of the short term SIR to the SIR target.