A material handling system has a vacuum cup assembly engagable with an object and movable to move the object using a pressurized air source, a vacuum cup, a venturi device and a vacuum valve and auto-release valve. The venturi device is in fluid communication with the vacuum cup and connected to the supply line so that pressurized air can be supplied to and through said venturi device to generate a partial vacuum when the perimeter seal of the vacuum cup is engaged with the object surface. The vacuum valve may open and close the supply line at a location upstream of the venturi device in response to a pressure level at the vacuum cup cavity. The auto-release valve may vent the vacuum cup cavity to atmosphere in response to reduced pressure in the supply line at a location upstream from the vacuum valve.