A method for manufacturing a membrane-electrode assembly of the present invention includes: a reinforcing member disposing step of disposing a reinforcing member (104A, 104B), whose frame portion is formed to surround an opening of the reinforcing member, on a polymer electrolyte membrane (102) such that the frame portion covers a peripheral portion of at least one surface of the polymer electrolyte membrane; a catalyst layer applying step of applying a coating of a catalyst layer (109A, 109B) on at least an entire surface of the polymer electrolyte membrane (102) which surface is exposed from the opening of the reinforcing member (104A, 104B); and a gas diffusion layer disposing step of disposing a gas diffusion layer (114A, 114B) such that the gas diffusion layer covers the catalyst layer (109A, 109B).