Invention Grant
- Patent Title: Methods and compositions for vitamin K epoxide reductase
- Patent Title (中): 维生素K环氧化物还原酶的方法和组成
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Application No.: US11924707Application Date: 2007-10-26
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Publication No.: US08097410B2Publication Date: 2012-01-17
- Inventor: Darrel W. Stafford , Tao Li
- Applicant: Darrel W. Stafford , Tao Li
- Applicant Address: US NC Chapel Hill
- Assignee: University of North Carolina at Chapel Hill
- Current Assignee: University of North Carolina at Chapel Hill
- Current Assignee Address: US NC Chapel Hill
- Agency: Myers Bigel Sibley & Sajovec, P.A.
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; C07H21/02 ; C07H21/04 ; C12P19/24

Abstract:
The present invention provides a method of identifying a human subject having increased or decreased sensitivity to warfarin, comprising detecting in the subject the presence of a single nucleotide polymorphism in the VKOR gene, wherein the single nucleotide polymorphism is correlated with increased or decreased sensitivity to warfarin, thereby identifying the subject having increased or decreased sensitivity to warfarin.
Public/Granted literature
- US20090215045A1 Methods and Compositions for Vitamin K Epoxide Reductase Public/Granted day:2009-08-27
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