Invention Grant
US08097595B2 Modulation of telomere length in telomerase positive cells and cancer therapy
有权
端粒酶阳性细胞和癌症治疗中端粒长度的调节
- Patent Title: Modulation of telomere length in telomerase positive cells and cancer therapy
- Patent Title (中): 端粒酶阳性细胞和癌症治疗中端粒长度的调节
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Application No.: US12662939Application Date: 2010-05-12
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Publication No.: US08097595B2Publication Date: 2012-01-17
- Inventor: Igor E. Bondarev
- Applicant: Igor E. Bondarev
- Applicant Address: US DE Wilmington
- Assignee: ALT Solutions, Inc.
- Current Assignee: ALT Solutions, Inc.
- Current Assignee Address: US DE Wilmington
- Agency: Stites & Harbison PLLC
- Agent Juan Carlos A. Marquez, Esq.
- Main IPC: A01N43/04
- IPC: A01N43/04 ; A61K31/70
Abstract:
Induction of telomere shortening, G2 arrest and apoptosis in telomerase positive cancer cells using acyclic nucleoside analogs has been disclosed. In addition, methods for impairment or prevention of tumorigenic telomerase positive cells from having a chance to grow into a tumor and methods for promoting tumor regression (decrease in size of an established tumor) using acyclic nucleoside analogs has been disclosed.
Public/Granted literature
- US20100227832A1 Modulation of telomere length in telomerase positive cells and cancer therapy Public/Granted day:2010-09-09
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