Invention Grant
- Patent Title: Sulfonyl-derivatives as novel or histone deacetylase
- Patent Title (中): 磺酰衍生物作为新的或组蛋白脱乙酰酶
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Application No.: US12759256Application Date: 2010-04-13
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Publication No.: US08097611B2Publication Date: 2012-01-17
- Inventor: Kristof Van Emelen , Janine Arts , Leo-Jacobus Jozef Backx , Hans Louis Jos De Winter , Sven Franciscus Anna Van Brandt , Marc Gustaaf Celine Verdonck , Lieven Meerpoel , Isabelle Noëlle Constance Pilatte , Virginie Sophie Poncelet , Alexey Borisovich Dyatkin , Jimmy Arnold Viviane Van heusden
- Applicant: Kristof Van Emelen , Janine Arts , Leo-Jacobus Jozef Backx , Hans Louis Jos De Winter , Sven Franciscus Anna Van Brandt , Marc Gustaaf Celine Verdonck , Lieven Meerpoel , Isabelle Noëlle Constance Pilatte , Virginie Sophie Poncelet , Alexey Borisovich Dyatkin , Jimmy Arnold Viviane Van heusden
- Applicant Address: BE Beerse
- Assignee: Janssen Pharmaceutica, N.V.
- Current Assignee: Janssen Pharmaceutica, N.V.
- Current Assignee Address: BE Beerse
- Agent Rajiv S. Shah
- Main IPC: A61K31/551
- IPC: A61K31/551 ; A61K31/5377 ; A61K31/506 ; A61K31/496 ; C07D243/08 ; C07D413/14 ; C07D403/04 ; C07D295/26
Abstract:
This invention comprises the novel compounds of formula (I) wherein n, m, t, R1, R2, R3, R4, L, Q, X, Y, Z and have defined meanings, having histone deacetylase inhibiting enzymatic activity; their preparation, compositions containing them and their use as a medicine.
Public/Granted literature
- US20100240639A1 Sulfonyl-Derivatives as Novel or Histone Deacetylase Public/Granted day:2010-09-23
Information query
