Invention Grant
US08097616B2 Process for preparation of high-purity meloxicam and meloxicam potassium salt
有权
制备高纯度美洛昔康和美洛昔康钾盐的方法
- Patent Title: Process for preparation of high-purity meloxicam and meloxicam potassium salt
- Patent Title (中): 制备高纯度美洛昔康和美洛昔康钾盐的方法
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Application No.: US11793548Application Date: 2005-12-16
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Publication No.: US08097616B2Publication Date: 2012-01-17
- Inventor: Tibor Mezei , Gyula Simig , Enikó Molnár , Gyula Lukács , Márta Porcs-Makkay , Balázs Volk , Valéria Hofmanné Fekete , Kálmán Nagy , Norbert Mesterházy , György Krasznai , Györgyi Vereczkeyné Donáth , Gyuláné Körtvélyessy , Éva Pécsi
- Applicant: Tibor Mezei , Gyula Simig , Enikó Molnár , Gyula Lukács , Márta Porcs-Makkay , Balázs Volk , Valéria Hofmanné Fekete , Kálmán Nagy , Norbert Mesterházy , György Krasznai , Györgyi Vereczkeyné Donáth , Gyuláné Körtvélyessy , Éva Pécsi
- Applicant Address: HU Budapest
- Assignee: Egis Gyogyszergyar Nyilvanosan Mukodo Reszvenytarsasag
- Current Assignee: Egis Gyogyszergyar Nyilvanosan Mukodo Reszvenytarsasag
- Current Assignee Address: HU Budapest
- Agent Jonathan Myers; Andrew Wilford
- Priority: HUP0402634 20041218
- International Application: PCT/HU2005/000136 WO 20051216
- International Announcement: WO2006/064298 WO 20060622
- Main IPC: C07D417/12
- IPC: C07D417/12 ; A61K31/427 ; A61P29/00
Abstract:
The invention provides a process for the preparation of high purity meloxicam of the Formula (II). The meloxicam raw product is reacted with the solution of potassium hydroxide or potassium carbonate, whereby high purity meloxicam potassium sait monohydrate is produced. Said sait is subsequently treated with mineral or organic acid to yield high-purity meloxicam.
Public/Granted literature
- US20090215757A1 Process for Preparation of High-Purity Meloxicam and Meloxicam Potassium Salt Public/Granted day:2009-08-27
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