Invention Grant
- Patent Title: Morpholinopurine derivatives
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Application No.: US12579175Application Date: 2009-10-14
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Publication No.: US08097622B2Publication Date: 2012-01-17
- Inventor: Kiyoshi Nakayama , Kazuyuki Sugita , Masaki Setoguchi , Yuichi Tominaga , Masanori Saitou , Takashi Odagiri
- Applicant: Kiyoshi Nakayama , Kazuyuki Sugita , Masaki Setoguchi , Yuichi Tominaga , Masanori Saitou , Takashi Odagiri
- Applicant Address: JP Chuo-ku
- Assignee: Daiichi Sankyo Company, Limited
- Current Assignee: Daiichi Sankyo Company, Limited
- Current Assignee Address: JP Chuo-ku
- Agency: Christensen O'Connor Johnson Kindness PLLC
- Priority: JP2008-264797 20081014; JP2009-121690 20090520
- Main IPC: A61K31/535
- IPC: A61K31/535 ; C07D413/14
Abstract:
There is provided a novel compound that inhibits phosphatidylinositol 3-kinase (PI3K) and/or the mammalian target of rapamycin (mTOR) and exhibits anti-tumor activity. The present invention provides a compound represented by the following formula (1) having various substituents that inhibits PI3K and/or mTOR and exhibits anti-tumor activity: wherein R1, R2, R3, R4, Ra, Rb, Rc, and X each have the same meaning as defined in the specification.
Public/Granted literature
- US20100130492A1 MORPHOLINOPURINE DERIVATIVES Public/Granted day:2010-05-27
Information query
