Invention Grant
US08097632B2 Inhibitors of hedgehog signaling pathways, compositions and uses related thereto
有权
刺猬蛋白信号通路抑制剂，组合物和与之相关的用途
- Patent Title: Inhibitors of hedgehog signaling pathways, compositions and uses related thereto
- Patent Title (中): 刺猬蛋白信号通路抑制剂，组合物和与之相关的用途
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Application No.: US11894712Application Date: 2007-08-20
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Publication No.: US08097632B2Publication Date: 2012-01-17
- Inventor: Philip A. Beachy , Jeffery A. Porter , Michael K. Cooper
- Applicant: Philip A. Beachy , Jeffery A. Porter , Michael K. Cooper
- Applicant Address: US MD Baltimore
- Assignee: Johns Hopkins University School of Medicine
- Current Assignee: Johns Hopkins University School of Medicine
- Current Assignee Address: US MD Baltimore
- Agency: Ropes & Gray LLP
- Main IPC: A61K31/44
- IPC: A61K31/44
Abstract:
The present invention makes available assays and reagents inhibiting paracrine and/or autocrine signals produced by a hedgehog protein or aberrant activation of a hedgehog signal transduction pathway, e.g., which involve the use of a steroidal alkaloid or other small molecule.
Public/Granted literature
- US20080058298A1 Inhibitors of hedgehog signaling pathways, compositions and uses related thereto Public/Granted day:2008-03-06
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