Invention Grant
US08097727B2 N,N′-diphenylurea derivatives which are suitable as kinase inhibitors
失效
N，N'-二苯基脲衍生物，其适合作为激酶抑制剂
- Patent Title: N,N′-diphenylurea derivatives which are suitable as kinase inhibitors
- Patent Title (中): N，N'-二苯基脲衍生物，其适合作为激酶抑制剂
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Application No.: US11665113Application Date: 2005-10-04
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Publication No.: US08097727B2Publication Date: 2012-01-17
- Inventor: Wolfgang Staehle , Guenter Hoelzemann , Wilfried Rautenberg
- Applicant: Wolfgang Staehle , Guenter Hoelzemann , Wilfried Rautenberg
- Applicant Address: DE
- Assignee: Merck patent GmbH
- Current Assignee: Merck patent GmbH
- Current Assignee Address: DE
- Agency: Perkins Coie LLP
- Priority: EP04024367 20041013
- International Application: PCT/EP2005/010660 WO 20051004
- International Announcement: WO2006/040039 WO 20060420
- Main IPC: C07D471/02
- IPC: C07D471/02
Abstract:
Compounds of the formula (I), in which R1a-R1e, R2a, R2b, R3 and R5 have the meanings indicated in claim 1, are inhibitors of tyrosine kinases, in particular TIE-2, and Raf kinases and can be employed, inter alia, for the treatment of tumors.
Public/Granted literature
- US20080114026A1 N,N'-Diphenylurea Derivatives Which are Suitable as Kinase Inhibitors Public/Granted day:2008-05-15
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