Invention Grant
- Patent Title: Iminosugar compounds with antiflavirus activity
- Patent Title (中): 具有抗病毒活性的Iminosugar化合物
-
Application No.: US12112694Application Date: 2008-04-30
-
Publication No.: US08097728B2Publication Date: 2012-01-17
- Inventor: Baohua Gu , Timothy M. Block , Robert M. Moriarty , Mahendra N. Deshpande , Rajendra C. Shah
- Applicant: Baohua Gu , Timothy M. Block , Robert M. Moriarty , Mahendra N. Deshpande , Rajendra C. Shah
- Applicant Address: US PA Philadelphia US IL Urbana
- Assignee: Philadelphia Health & Education Corporation,The Board Of Trustees Of The University of Illinois
- Current Assignee: Philadelphia Health & Education Corporation,The Board Of Trustees Of The University of Illinois
- Current Assignee Address: US PA Philadelphia US IL Urbana
- Agency: Woodcock Washburn, LLP
- Main IPC: C12N9/99
- IPC: C12N9/99 ; A61P31/14 ; C07D211/40

Abstract:
An anti-viral compounds effective against viruses belonging to the Flaviviridae family, wherein the anti-viral compounds are 1,5-dideoxy-1,5-imino-D-glucitol derivative compounds having the general formula (I) wherein R2, R3, R4 and R5 are the same or different and are selected from the group consisting of hydrogen, acyl, benzyl, alkyl, aryl, sulfonyl, phosphonyl, silyl, R6 is at least one of alkyl or branched alkyl, heteroalkyl or aryl, R6′ is a bridging group selected from at least one of bicycle[2.2.1]heptyl, bicycle[3.2.1]octyl, oxa analogs, admonyl and cubyl, n′=2-10, n″=1-10, enantiomers and stereoisomers of said compounds and physiologically acceptable salts or solvates of said compounds, enantiomer or stereoisomer.
Public/Granted literature
- US20090042268A1 IMINOSUGAR COMPOUNDS WITH ANTIFLAVIRUS ACTIVITY Public/Granted day:2009-02-12
Information query