Among various ions introduced into an ion trap 1, those ions which are within a predetermined mass range including the mass-to-charge ratio of an objective ion are selected. Then, the frequency of a capturing voltage is set so that the objective ion will be captured with a high q-value, and a CID gas is introduced into the ion trap 1. An excitation voltage corresponding to the mass-to-charge ratio of the objective ion is applied to end-cap electrodes 3 and 4 to cause an oscillation of the objective ion and help dissociation of the ion by CID. The high q-value leads to a high dissociation efficiency. The application of the excitation voltage is discontinued before the low-mass ions produced by CID totally dissipate. Simultaneously with this operation, or slightly delayed therefrom, the frequency of the capturing voltage is switched so that the q-value will be lowered. Although the high q-value allows the low-mass product ions to easily dissipate during the CID process, they can be captured within an ion-trapping space 5 since the q-value is lowered when those ions still remain there. Thus, measurement of low-mass product ions can be simultaneously achieved with improvement of dissociation efficiency.