This invention provides a tire monitoring system, comprising a remote tire monitoring unit installed in the tire, a central controller, a speech indicating unit and a brake deceleration mechanism; wherein the remote tire monitoring unit is used to monitor and sample the pressure and temperature within the tire, and generate the sampling data signals of tire conditions which are subsequently wirelessly transmitted to the central controller; the central controller wirelessly receives sampling data signals of tire conditions, and calculates received data signals so as to generate speech indicating command and/or brake deceleration command, and afterward conveys the speech indicating command to the speech indicating unit, while the brake deceleration command to the brake deceleration mechanism; a speech indication unit, provided to receive said speech indication command and output the speech indication information; and a brake deceleration mechanism, provided to receive said brake deceleration command and performs action of brake deceleration so as to provide effective security protection when quick deflation and tire burst suddenly occur in a short time.