A post-operative pain inhibitor system (100) comprises a controller (32) and leads (25, 27). Neuro-stimulator circuitry may be included within the patient controller 32 or within one or more prosthetic components (12, 13, 14) for generating a signal. The topical leads (27), percutaneous leads (25), subcutaneous leads (26), intraosseous leads (22) or leads placed on or within prosthetic components are coupled to neuro-stimulation circuitry (44) to stimulate peripheral nerve fibers such that the signal blocks body generated action potentials. Controller (32) can modify the pulse width, pulse shape, pulse repetition rate, and pulse amplitude of the signal thereby allowing the patient to adapt the signal to minimize their perceived pain.