Invention Grant
- Patent Title: Crystallographic structure of Trypanosoma cruzi proline racemase and uses therefor
- Patent Title (中): 锥虫脯氨酸消旋酶的晶体结构及其用途
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Application No.: US10558371Application Date: 2004-06-01
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Publication No.: US08099245B2Publication Date: 2012-01-17
- Inventor: Paola Minoprio , Pedro Alzari , Alejandro Buschiazzo , Wim Degrave , Christophe Gregoire , Nathalie Chamond , Armand Berneman
- Applicant: Paola Minoprio , Pedro Alzari , Alejandro Buschiazzo , Wim Degrave , Christophe Gregoire , Nathalie Chamond , Armand Berneman
- Applicant Address: FR Paris FR Paris
- Assignee: Institut Pasteur,Centre National de la Recherche Scientifique
- Current Assignee: Institut Pasteur,Centre National de la Recherche Scientifique
- Current Assignee Address: FR Paris FR Paris
- Agency: Finnegan, Henderson, Farabow, Garrett & Dunner LLP
- International Application: PCT/IB2004/002062 WO 20040601
- International Announcement: WO2004/106506 WO 20041209
- Main IPC: G01N31/00
- IPC: G01N31/00 ; G01N33/53 ; G01N33/567 ; G06G7/58 ; C12Q1/00
Abstract:
The present invention provides the crystal structure of the Trypanosoma cruzi PRACA proline racemase. Methods of modelling drugs that treat or prevent infection by T. cruzi are also provided, as are the drugs that are identified.
Public/Granted literature
- US20080113422A1 Crystallographic Structure Of Tcpraca And Uses Therefor Public/Granted day:2008-05-15
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