An integrated circuit is divided into two or more different regions, each region being a different voltage domain. In each of the regions, a voltage drop and its impact on performance will be quantified. A place and route engine (or another tool of a computer-aided design flow) will then take these timing considerations into account while performing partitioning of the device. A user's logic design is implemented into the logic array blocks taking into a voltage drop seen at those logic array blocks. Faster paths of the logic design are placed into faster logic array blocks, such as those in a core region of the integrated circuit.