A pipe handling system includes a lifting mechanism coupled to an upper end of a pipe above a free end of the pipe, and a guide system operable to engage the pipe and control lateral movement of the pipe as it is moved between a storage position and a well center position, the guide system including a pair of support members including extendable end portions and a flexible pipe guide coupled between the extendable end portions. In some embodiments, the guide system includes a pair of rotatable support arms having first pivot ends and second ends and an expandable pipe guide connecting the second ends.