Invention Grant
- Patent Title: Coiled wire for the controlled release of drugs to the eye
- Patent Title (中): 用于控制释放药物的线圈用于眼睛
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Application No.: US11994934Application Date: 2006-06-30
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Publication No.: US08109913B2Publication Date: 2012-02-07
- Inventor: Aylvin Jorge Angelo Athanasius Dias , Levinus Hendrik Koole , Rachel Theodora Pijls
- Applicant: Aylvin Jorge Angelo Athanasius Dias , Levinus Hendrik Koole , Rachel Theodora Pijls
- Applicant Address: NL Heerlen
- Assignee: DSM IP Assets B.V.
- Current Assignee: DSM IP Assets B.V.
- Current Assignee Address: NL Heerlen
- Agency: Nixon & Vanderhye P.C.
- Priority: EP05076580 20050711; EP05077210 20050927
- International Application: PCT/EP2006/006355 WO 20060630
- International Announcement: WO2007/006427 WO 20070118
- Main IPC: A61M35/00
- IPC: A61M35/00 ; A61F2/00 ; A61F9/00

Abstract:
This invention is in the area of medical devices, in particular in the area of medical devices for drug delivery, more in particular for controlled release of drugs to the eye. Delivery of drugs to the anterior side of the eye is routinely done with eye drops, but this method results in low bioavailability and low patient compliance. Devices that address these problems have been described for the delivery of drugs to the eye. One of such devices, called the OphthaCoil, consists of a thin metallic wire, which is coiled and carries a drug-loaded adherent hydrogel coating on its surface. Surprisingly it has now been found that the drug loading capacity can be dramatically increased by filling the lumen of the coil with micro-particles such as microspheres that contain the drug of choice.
Public/Granted literature
- US20090143747A1 COILED WIRE FOR THE CONTROLLED RELEASE OF DRUGS TO THE EYE Public/Granted day:2009-06-04
Information query
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