Certain example embodiments relate to articles supporting photocatalytic layers that also include UV-reflecting underlayers, and/or methods of making the same. In certain example embodiments, the inclusion of a UV-reflecting underlayer surprisingly and unexpectedly results in the reduction of dosing time to enable quick activation of the photocatalytic coating. For example, dosing time may be reduced from a few hours to a few minutes or even seconds in certain example embodiments. The UV-reflecting underlayer may be a single-layer coating or a multi-layer stack.