Invention Grant
- Patent Title: HGF β chain variants
- Patent Title (中): HGF＆bgr 链变体
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Application No.: US12768557Application Date: 2010-04-27
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Publication No.: US08110377B2Publication Date: 2012-02-07
- Inventor: Daniel K. Kirchhofer , Robert A. Lazarus , Christian Wiesmann
- Applicant: Daniel K. Kirchhofer , Robert A. Lazarus , Christian Wiesmann
- Applicant Address: US CA South San Francisco
- Assignee: Genentech, Inc.
- Current Assignee: Genentech, Inc.
- Current Assignee Address: US CA South San Francisco
- Agent Stephanie Yonker
- Main IPC: A61K38/18
- IPC: A61K38/18 ; C07K14/475 ; C07H21/04 ; C12P21/06
Abstract:
The invention provides HGF/Met modulators comprising HGF having mutations in regions that affect HGF function, and antagonists that target said regions. The invention further provides methods of identifying, making and using these modulators.
Public/Granted literature
- US20100210826A1 HGF BETA CHAIN VARIANTS Public/Granted day:2010-08-19
Information query
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