Invention Grant
- Patent Title: Degradation and detection of TSE infectivity
- Patent Title (中): 降解和检测TSE感染性
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Application No.: US11871087Application Date: 2007-10-11
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Publication No.: US08110391B2Publication Date: 2012-02-07
- Inventor: Neil David Hammond Raven , John Mark Sutton
- Applicant: Neil David Hammond Raven , John Mark Sutton
- Applicant Address: GB Salisbury, Wiltshire
- Assignee: Health Protection Agency
- Current Assignee: Health Protection Agency
- Current Assignee Address: GB Salisbury, Wiltshire
- Agency: Evan Law Group LLC
- Priority: GB0100420.9 20010108; GB0104696.0 20010226; GBPCT/GB02/00052 20020108; GB0216146.1 20020711
- Main IPC: C02F3/34
- IPC: C02F3/34 ; C12S3/00 ; C12S9/00 ; D06M16/00

Abstract:
A transmissible spongiform encephalopathy (TSE) agent is inactivated by exposing the TSE agent to a thermostable proteolytic enzyme at elevated temperature and at acid or alkaline pH. Following this step, or separately, presence of TSE infectivity is detected by detection of dimers of prion protein.
Public/Granted literature
- US20080178306A1 DEGRADATION AND DETECTION OF TSE INFECTIVITY Public/Granted day:2008-07-24
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