Invention Grant
- Patent Title: Stable cell lines and methods for evaluating gastrointestinal absorption of chemicals
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Application No.: US12843706Application Date: 2010-07-26
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Publication No.: US08110398B2Publication Date: 2012-02-07
- Inventor: Albert J. Owen, III , Ismael J. Hidalgo , Jibin Li , Wei Zhang
- Applicant: Albert J. Owen, III , Ismael J. Hidalgo , Jibin Li , Wei Zhang
- Applicant Address: US PA Exton
- Assignee: Absorption Systems Group, LLC
- Current Assignee: Absorption Systems Group, LLC
- Current Assignee Address: US PA Exton
- Agency: Woodcock Washburn LLP
- Main IPC: C07H21/02
- IPC: C07H21/02 ; C07H21/04 ; C12N15/00 ; C12Q1/68
Abstract:
Nucleic acids and vectors for interfering with the expression of membrane efflux transport proteins in cells that express such proteins are provided. Also provided are cells and cell lines comprising such nucleic acids and vectors. Methods for screening chemicals and biomolecules for gastrointestinal absorption in animals, and kits for practicing such methods are also provided.
Public/Granted literature
- US20100311082A1 Stable Cell Lines and Methods for Evaluating Gastrointestinal Absorption of Chemicals Public/Granted day:2010-12-09
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