Invention Grant
- Patent Title: Method for treating cartilage disorders
- Patent Title (中): 软骨疾病治疗方法
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Application No.: US11934582Application Date: 2007-11-02
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Publication No.: US08110548B2Publication Date: 2012-02-07
- Inventor: Yvonne Man-Yee Chen , Ross G. Clark , Andrea G. Cochran , Yves Dubaquie , Paul J. Fielder , Ellen Filvaroff , Henry B. Lowman , Deborah L. Mortensen , Iain C. A. F. Robinson , Nicholas J. Skelton
- Applicant: Yvonne Man-Yee Chen , Ross G. Clark , Andrea G. Cochran , Yves Dubaquie , Paul J. Fielder , Ellen Filvaroff , Henry B. Lowman , Deborah L. Mortensen , Iain C. A. F. Robinson , Nicholas J. Skelton
- Applicant Address: US CA South San Francisco
- Assignee: Genentech, Inc.
- Current Assignee: Genentech, Inc.
- Current Assignee Address: US CA South San Francisco
- Agency: Arnold & Porter LLP
- Agent Craig Svoboda; Ginger R. Dreger
- Main IPC: A61K38/00
- IPC: A61K38/00
Abstract:
The present invention relates to a method for the treatment of a cartilage disorder, including cartilage damaged by injury or degenerative cartilagenous disorders. The method involves contacting the cartilage with an IGF-1 analog with altered affinity for IGF-binding proteins (IGFBPs) or an IGFBP displacer peptide that prevents the interaction of an IGF with an IGFBP and does not bind to a human IGF receptor.
Public/Granted literature
- US20100130411A1 METHOD FOR TREATING CARTILAGE DISORDERS Public/Granted day:2010-05-27
Information query
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