Invention Grant
- Patent Title: Gamma secretase inhibitor for treatment of herpesvirus infection
- Patent Title (中): γ分泌酶抑制剂治疗疱疹病毒感染
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Application No.: US11822419Application Date: 2007-07-05
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Publication No.: US08110557B2Publication Date: 2012-02-07
- Inventor: Erle S. Robertson , Ke Lan
- Applicant: Erle S. Robertson , Ke Lan
- Applicant Address: US PA Philadelphia
- Assignee: The Trustees of the University of Pennsylvania
- Current Assignee: The Trustees of the University of Pennsylvania
- Current Assignee Address: US PA Philadelphia
- Agency: Pearl Cohen Zedek Latzer, LLP
- Agent Mark S. Cohen
- Main IPC: A61K31/70
- IPC: A61K31/70 ; C12Q1/68
Abstract:
This invention relates to methods and compositions for the treatment of malignancies associated with gamma-herpesvirus infection. Specifically, the invention relates to the use of gamma-secretase inhibitors to prevent the production of intracellular Notch1 thereby arresting the growth of the infected cells.
Public/Granted literature
- US20090060881A1 Gamma secretase inhibitor for treatment of herpesvirus infection Public/Granted day:2009-03-05
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