Invention Grant
- Patent Title: Lactam compounds and their use as pharmaceuticals
- Patent Title (中): 内酰胺化合物及其作为药物的用途
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Application No.: US12252700Application Date: 2008-10-16
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Publication No.: US08110581B2Publication Date: 2012-02-07
- Inventor: Wenqing Yao , Chunhong He , David M. Burns , Jincong Zhuo , Meizhong Xu , Colin Zhang , Ding-Quan Qian , Brian Metcalf
- Applicant: Wenqing Yao , Chunhong He , David M. Burns , Jincong Zhuo , Meizhong Xu , Colin Zhang , Ding-Quan Qian , Brian Metcalf
- Applicant Address: US DE Wilmington
- Assignee: Incyte Corporation
- Current Assignee: Incyte Corporation
- Current Assignee Address: US DE Wilmington
- Agency: Fish & Richardson P.C.
- Main IPC: C07D471/10
- IPC: C07D471/10 ; A61K31/4439
Abstract:
The present invention relates to inhibitors of 11-βhydroxyl steroid dehydrogenase type 1, antagonists of the mineralocorticoid receptor (MR), and pharmaceutical compositions thereof. The compounds of the invention can be useful in the treatment of various diseases associated with expression or activity of 11-βhydroxyl steroid dehydrogenase type 1 and/or diseases associated with aldosterone excess.
Public/Granted literature
- US20090291946A1 LACTAM COMPOUNDS AND THEIR USE AS PHARMACEUTICALS Public/Granted day:2009-11-26
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