Invention Grant
- Patent Title: Bicyclic compound and pharmaceutical use thereof
- Patent Title (中): 双环化合物及其药物用途
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Application No.: US12451090Application Date: 2008-04-25
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Publication No.: US08110585B2Publication Date: 2012-02-07
- Inventor: Tatsuki Koike , Takafumi Takai , Yasutaka Hoashi
- Applicant: Tatsuki Koike , Takafumi Takai , Yasutaka Hoashi
- Applicant Address: JP Osaka
- Assignee: Takeda Pharmaceutical Company Limited
- Current Assignee: Takeda Pharmaceutical Company Limited
- Current Assignee Address: JP Osaka
- Agency: Wenderoth, Lind & Ponack, L.L.P.
- Priority: JP2007/117676 20070426
- International Application: PCT/JP2008/058020 WO 20080425
- International Announcement: WO2008/136382 WO 20081113
- Main IPC: A61K31/416
- IPC: A61K31/416 ; A61K31/428 ; A61K31/437 ; C07D231/54 ; C07D277/64 ; C07D471/04

Abstract:
The present invention provides a compound represented by the formula wherein R1 is a hydrocarbon group optionally having substituent(s), amino optionally having substituent(s), hydroxy optionally having a substituent or a heterocyclic group optionally having substituent(s); R2 is a hydrogen atom or a hydrocarbon group optionally having substituent(s); Xa and Xb are each C, N, O or S; Xc and Xd are each C or N; m is 0-2; n is 1-3; ring A is a 5-membered ring optionally having substituent(s); ring B is a 6-membered ring optionally having substituent(s); and ring C is a 3- to 5-membered ring optionally having substituent(s), provided that when Xa, Xc and Xd are each C, then Xb is N or S, or a salt thereof, which is useful as an agent for the prophylaxis or treatment of a disease relating to an action of melatonin, and the like.
Public/Granted literature
- US20100130538A1 BICYCLIC COMPOUND AND PHARMACEUTICAL USE THEREOF Public/Granted day:2010-05-27
Information query
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