Invention Grant
US08110654B2 T cell epitope peptides of ovarian cancer anti-idiotypic antibody 6B11 and use thereof
有权
卵巢癌抗独特型抗体6B11的T细胞表位肽及其用途
- Patent Title: T cell epitope peptides of ovarian cancer anti-idiotypic antibody 6B11 and use thereof
- Patent Title (中): 卵巢癌抗独特型抗体6B11的T细胞表位肽及其用途
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Application No.: US12303244Application Date: 2007-06-04
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Publication No.: US08110654B2Publication Date: 2012-02-07
- Inventor: Heng Cui , Wei Li , Xiaohong Chang , Jie Feng , Hongyan Cheng , Huifang Guo , Yexia Cheng
- Applicant: Heng Cui , Wei Li , Xiaohong Chang , Jie Feng , Hongyan Cheng , Huifang Guo , Yexia Cheng
- Applicant Address: CN Beijing
- Assignee: Peking University People;s Hospital
- Current Assignee: Peking University People;s Hospital
- Current Assignee Address: CN Beijing
- Agency: Perkins Coie LLP
- Agent Yingli Wang
- Priority: CN200610083299 20060602
- International Application: PCT/CN2007/001769 WO 20070604
- International Announcement: WO2007/143917 WO 20071221
- Main IPC: A61K38/00
- IPC: A61K38/00 ; C07K2/00 ; C07K4/00 ; C07K5/00 ; C07K7/00 ; C07K14/00 ; C07K16/00 ; C07K17/00 ; A61K38/04 ; A61K38/10 ; A61K38/08 ; A61P35/00
Abstract:
The present invention provides two T-cell epitode peptides of anti-idiotype antibody 6B11 of ovarian cancer, the sequences of which are shown in SEQ ID NO:3 or 6. The present invention also provides the use of such T-cell epitope peptides in the manufacture of vaccines against ovarian cancer and in the treatment and prevention of ovarian cancer. The T-cell epitope peptides of the present invention could specifically kill ovarian cancer cells which are OC166-9 positive, and could find a wide use in the treatment and prevention of ovarian cancer.
Public/Granted literature
- US20090269366A1 T CELL EPITOPE PEPTIDES OF 6B11 OVARIAN CANCER ANTI-IDIOTYPIC ANTIBODY Public/Granted day:2009-10-29
Information query
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