Invention Grant
- Patent Title: Anti-IP-10 antibodies and methods of use thereof
- Patent Title (中): 抗IP-10抗体及其使用方法
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Application No.: US12871387Application Date: 2010-08-30
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Publication No.: US08110661B2Publication Date: 2012-02-07
- Inventor: Nicolas Fischer , Marie Kosco-Vilbois , Olivier Leger
- Applicant: Nicolas Fischer , Marie Kosco-Vilbois , Olivier Leger
- Applicant Address: CH Geneva
- Assignee: Novlmmune S.A.
- Current Assignee: Novlmmune S.A.
- Current Assignee Address: CH Geneva
- Agency: Mintz Levin Cohn Ferris Glovsky and Popeo, P.C.
- Agent Ivor R. Elrifi
- Main IPC: C07K16/00
- IPC: C07K16/00 ; C12P21/08 ; A61K39/395 ; A61K39/40 ; C07K17/00

Abstract:
The invention relates to fully human antibodies, and fragments thereof, that bind to interferon-inducible-protein-10 (IP-10, CXCL10), thereby modulating the interaction between IP-10 and its receptor, CXCR3, and/or modulating the biological activities of IP-10. The invention also relates to the use of such anti-IP-10 antibodies in the prevention or treatment of immune-related disorders and in the amelioration of one or more symptoms associated with an immune-related disorder.
Public/Granted literature
- US20100330094A1 Anti-IP-10 Antibodies and Methods of Use Thereof Public/Granted day:2010-12-30
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