Invention Grant
- Patent Title: Monoclonal antibodies for cartillage oligomeric matrix protein
- Patent Title (中): 用于软骨寡聚基质蛋白的单克隆抗体
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Application No.: US12768614Application Date: 2010-04-27
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Publication No.: US08110663B2Publication Date: 2012-02-07
- Inventor: Dick Heinegård
- Applicant: Dick Heinegård
- Applicant Address: SE Gothenburg
- Assignee: AnaMar AB
- Current Assignee: AnaMar AB
- Current Assignee Address: SE Gothenburg
- Agency: Wolf, Greenfield & Sacks, P.C.
- Priority: SE9904236 19991122
- Main IPC: G01N33/533
- IPC: G01N33/533
Abstract:
The present invention provides a new sensitive direct sandwich assay for determining the presence of COMP in a clinical sample. Two monoclonal antibodies directed against separate antigenic determinants of the COMP molecules are used in the assay. The invention also relates to three particularly advantageous monoclonal antibodies per se that are directed against human COMP. Cell cultures manufacturing these antibodies have been deposited according to the Budapest Treaty at Deutsche Sammlung von Mikroorganismen and Zellkulturen GmbH, and have been assigned accesion numbers DSM ACC2406, DSM ACC2408 and DSM ACC2418, respectively. A diagnostic kit comprising at least two of these monoclonal antibodies also constitute a part of the present invention.
Public/Granted literature
- US20100210039A1 SANDWICH IMMUNOASSAY AND MONOCLONAL ANTIBODIES FOR COMP, CARTILLAGE OLIGOMERIC MATRIX PROTEIN Public/Granted day:2010-08-19
Information query
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